Drug receives breakthrough designation for relapsed/refractory AML

AML cells
The US Food and Drug Administration (FDA) has granted GMI-1271 breakthrough therapy designation for the treatment of adults with relapsed/refractory acute myeloid leukemia (AML). GMI-1271 is an E-selectin antagonist being developed by GlycoMimetics, Inc. The product already has orphan and fast track designations from the FDA for the treatment of AML. GMI-1271... [Read Article]

Single-cell analysis reveals TKI-resistant CML stem cells

CML cells
Image by Difu Wu
Researchers say they’ve developed a technique for single-cell analysis that has revealed a population of treatment-resistant stem cells in patients with chronic myeloid leukemia (CML). “It is increasingly recognized that tumors contain a variety of different cell types, including so-called cancer stem cells, that drive the growth... [Read Article]

Videos reduce need for anesthesia in kids undergoing radiotherapy

Child watches a movie while
undergoing radiotherapy
Photo from VLADI project
Children with cancer may not require general anesthesia prior to radiotherapy if they can watch videos during their treatment, according to research presented at the ESTRO 36 conference (abstract OC-0546). Allowing children to watch videos during radiotherapy reduced but did not completely... [Read Article]