Better matching for blood transfusions

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Blood for transfusion
Photo by Elise Amendola
Researchers have developed software that could enable more precise matching for blood transfusions, according to a paper published in The Lancet Haematology. The software, bloodTyper, can automatically type red blood cell (RBC) and platelet antigens from whole-genome sequencing (WGS) data. In repeated tests, bloodTyper produced results that... [Read Article]
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FDA approves new use for Zika test

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Blood for transfusion
Photo from UAB Hospital
The US Food and Drug Administration (FDA) has approved an additional use for the cobas Zika test. The approval allows for the streamlined screening of multiple individual blood or plasma donations that have been pooled together. The cobas Zika test is a qualitative in vitro nucleic acid screening... [Read Article]
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Producing compatible RBCs for transfusion

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Red blood cells
Researchers say they have found a way to generate customized red blood cells (RBCs) that might one day be used to avoid transfusion incompatibilities. The team used genome editing to modify an erythroblast cell line, making it deficient in antigens responsible for common transfusion incompatibilities. The cells in this line could... [Read Article]
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Health Canada approves blood system for platelets

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Platelets for transfusion
Photo from Flickr
Health Canada has approved commercialization of the INTERCEPT Blood System for platelets, which is used for the ex vivo treatment and storage of platelet components. The INTERCEPT Blood System for platelets can inactivate a range of pathogens—including viruses, bacteria, and protozoan parasites—to reduce the risk of transfusion-transmitted infections.... [Read Article]
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