Intervention helps kids stay active after cancer treatment

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Child with leukemia
Photo by Bill Branson
Results of a pilot study suggest a web-based, reward-driven intervention can motivate adolescent cancer survivors to stay physically active. Time spent performing moderate-to-vigorous physical activity (MVPA) increased by an average of 5 minutes a week for subjects who were randomized to the intervention. For control subjects,... [Read Article]
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Young kids with SCA not receiving recommended prophylaxis

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Doctor examines
sickle cell patient
Photo from St. Jude
Children’s Research Hospital
Many young children with sickle cell anemia (SCA) may not be taking the recommended antibiotics to prevent invasive pneumococcal disease (IPD), according to research published in Pediatrics. Results of a previous study indicated that daily treatment with penicillin could reduce the... [Read Article]
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Child’s cancer diagnosis can affect mother’s income long-term

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Child with cancer
Photo by Bill Branson
A study conducted in Sweden revealed that social benefits can ease financial burdens for parents of children recently diagnosed with cancer. However, the study also showed that mothers experienced persistently lower income after benefits diminished. Ayako Hiyoshi, PhD, of Örebro University in Örebro, Sweden, and her... [Read Article]
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CAR T-cell therapy on fast track in US, EU

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Tisagenlecleucel (Kymriah)
Photo from Novartis
The chimeric antigen receptor (CAR) T-cell therapy tisagenlecleucel (Kymriah, formerly CTL019) is getting fast-tracked in the United States (US) and European Union (EU). The US Food and Drug Administration (FDA) has accepted for priority review the supplemental biologics license application (sBLA) for tisagenlecleucel for the treatment of adults... [Read Article]
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Gene variants associated with high-risk pediatric ALL

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Jun J. Yang, PhD
Photo from Seth Dixon,
St. Jude Children’s
Research Hospital
New research has revealed germline variations associated with high-risk acute lymphoblastic leukemia (ALL) in children. Researchers sequenced the TP53 tumor suppressor gene in nearly 4000 children with ALL and identified 22 pathogenic germline variants. These variants were associated with inferior survival... [Read Article]
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